ATG4C 抗体 (AA 259-458)
Quick Overview for ATG4C 抗体 (AA 259-458) (ABIN7149025)
抗原
See all ATG4C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 259-458
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交叉反应
- 人, 小鼠
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Cysteine protease ATG4C protein (259-458AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))
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别名
- ATG4C
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背景
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Background: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation (By similarity). Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Aliases: APG4 autophagy 4 homolog C (S. cerevisiae) antibody, APG4 autophagy 4 homolog C antibody, APG4 C antibody, APG4-C antibody, APG4C antibody, ATG 4C antibody, ATG4 autophagy related 4 homolog C (S. cerevisiae) antibody, ATG4 autophagy related 4 homolog C antibody, Atg4c antibody, ATG4C_HUMAN antibody, AUT (S. cerevisiae) like 1, cysteine endopeptidase antibody, AUT like 1, cysteine endopeptidase (S. cerevisiae) antibody, AUT like 1, cysteine endopeptidase antibody, AUT like 3 cysteine endopeptidase antibody, AUT-like 3 cysteine endopeptidase antibody, AUTL1 antibody, AUTL3 antibody, Autophagin 3 antibody, Autophagin-3 antibody, Autophagy related 4C cysteine peptidase antibody, Autophagy related cysteine endopeptidase 3 antibody, Autophagy related protein 4 homolog C antibody, Autophagy-related cysteine endopeptidase 3 antibody, Autophagy-related protein 4 homolog C antibody, Cysteine protease ATG4C antibody, EC 3.4.22 antibody, FLJ14867 antibody, OTTHUMP00000010715 antibody
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UniProt
- Q96DT6
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途径
- Autophagy
抗原
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