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p21 抗体 (AA 2-164)

This anti-p21 antibody is a 兔 多克隆 antibody detecting p21 in IHC, IF 和 ELISA. Suitable for 人.
产品编号 ABIN7148907
发货至: 中国

Quick Overview for p21 抗体 (AA 2-164) (ABIN7148907)

抗原

See all p21 (CDKN1A) 抗体
p21 (CDKN1A) (Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A))

适用

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宿主

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克隆类型

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多克隆

标记

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This p21 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA
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    AA 2-164

    原理

    CDKN1A Antibody

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Cyclin-dependent kinase inhibitor 1 protein (2-164AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    p21 (CDKN1A) (Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A))

    别名

    CDKN1A

    背景

    Background: May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex.

    Aliases: CAP20 antibody, CDK-interacting protein 1 antibody, CDKI antibody, CDKN1 antibody, Cdkn1a antibody, CDN1A_HUMAN antibody, CIP1 antibody, Cyclin Dependent Kinase Inhibitor 1A antibody, Cyclin-dependent kinase inhibitor 1 antibody, Cyclin-dependent kinase inhibitor 1A (P21) antibody, Cyclin-dependent kinase inhibitor 1A (p21, Cip1) antibody, DNA Synthesis Inhibitor antibody, MDA-6 antibody, MDA6 antibody, Melanoma differentiation-associated protein 6 antibody, Melanoma differentiation-associated protein antibody, p21 antibody, P21 protein antibody, p21CIP1 antibody, p21Cip1/Waf1 antibody, p21WAF antibody, PIC1 antibody, SDI1 antibody, SLC12A9 antibody, WAF1 antibody, Wild type p53 activated fragment 1 (WAF1) antibody, Wild type p53 activated fragment 1 antibody, Wildtype p53-activated fragment 1 antibody

    UniProt

    P38936

    途径

    p53 Pathway, PI3K-Akt Signaling, Cell Division Cycle, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Hepatitis C, Synthesis of DNA, Autophagy
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