COPS7B 抗体 (AA 1-157)
Quick Overview for COPS7B 抗体 (AA 1-157) (ABIN7148503)
抗原
See all COPS7B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-157
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交叉反应
- 人, 小鼠
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human COP9 signalosome complex subunit 7b protein (1-157AA)
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亚型
- IgG
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anti-COP9 Signalosome Complex Subunit 7b (COPS7B) (AA 61-95) antibody
COPS7B 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB56230 unconjugated
anti-COP9 Signalosome Complex Subunit 7b (COPS7B) (AA 1-264) antibodyCOPS7B 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-COP9 Signalosome Complex Subunit 7b (COPS7B) (AA 223-257) antibodyCOPS7B 适用: 人 WB 宿主: 兔 Polyclonal RB56231 unconjugated
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应用备注
- Recommended dilution: WB:1:2000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- COPS7B (COP9 Signalosome Complex Subunit 7b (COPS7B))
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别名
- COPS7B
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背景
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Background: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
Aliases: COP9 Complex Homolog Subunit 7b antibody, COP9 Constitutive Photomorphogenic Homolog Subunit 7b antibody, COP9 Signalasome Subunit 7b antibody, COP9 signalosome complex subunit 7b antibody, COPS7B antibody, CSN7B_HUMAN antibody, JAB1 Containing Signalosome Subunit 7b antibody, JAB1-containing signalosome subunit 7b antibody, SGN7b antibody, Signalosome subunit 7b antibody
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UniProt
- Q9H9Q2
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途径
- Cell Division Cycle
抗原
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