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Claudin 1 抗体 (AA 24-161) (FITC)

This FITC-conjugated 兔 多克隆 anti-Claudin 1 antibody specifically detects Claudin 1 in not_set. The antibody is reactive with 人 samples.
产品编号 ABIN7147873
发货至: 中国
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Quick Overview for Claudin 1 抗体 (AA 24-161) (FITC) (ABIN7147873)

抗原

See all Claudin 1 (CLDN1) 抗体
Claudin 1 (CLDN1)

适用

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宿主

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克隆类型

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多克隆

标记

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This Claudin 1 antibody is conjugated to FITC

应用范围

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  • 抗原表位

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    AA 24-161

    原理

    CLDN1 Antibody, FITC conjugated

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Claudin-1 protein (24-161AA)

    亚型

    IgG
  • 限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    Claudin 1 (CLDN1)

    别名

    CLDN1

    背景

    Background: Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. Required for normal water homeostasis and to prevent excessive water loss through the skin, probably via an indirect effect on the expression levels of other proteins, since CLDN1 itself seems to be dispensable for water barrier formation in keratinocyte tight junctions (PubMed:23407391).

    Aliases: Claudin-1 antibody, Claudin1 antibody, CLD 1 antibody, CLD1 antibody, CLD1_HUMAN antibody, CLDN 1 antibody, Cldn1 antibody, ILVASC antibody, SEMP 1 antibody, SEMP1 antibody, Senescence associated epithelial membrane protein 1 antibody, Senescence associated epithelial membrane protein antibody, Senescence-associated epithelial membrane protein antibody

    UniProt

    O95832

    途径

    Cell-Cell Junction Organization, Hepatitis C
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