CARD16 抗体 (AA 1-197)
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北京 101111
Quick Overview for CARD16 抗体 (AA 1-197) (ABIN7146911)
抗原
See all CARD16 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-197
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原理
- CARD16 Antibody
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Caspase recruitment domain-containing protein 16 protein (1-197AA)
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亚型
- IgG
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anti-Caspase Recruitment Domain Family, Member 16 (CARD16) antibody
CARD16 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 16 (CARD16) (AA 1-97) antibodyCARD16 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 16 (CARD16) (AA 1-97) antibodyCARD16 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Caspase Recruitment Domain Family, Member 16 (CARD16) (AA 1-97) antibodyCARD16 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 3E10 unconjugated
anti-Caspase Recruitment Domain Family, Member 16 (CARD16) (AA 44-73), (N-Term) antibodyCARD16 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CARD16 (Caspase Recruitment Domain Family, Member 16 (CARD16))
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别名
- CARD16
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背景
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Background: Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.
Aliases: CAR16_HUMAN antibody, CARD only domain-containing protein 1 antibody, CARD only protein antibody, CARD16 antibody, Caspase recruitment domain family, member 16 antibody, Caspase recruitment domain-containing protein 16 antibody, Caspase-1 dominant-negative inhibitor pseudo-ICE antibody, Caspase-1 inhibitor COP antibody, COP antibody, COP1 antibody, Pseudo interleukin 1 beta converting enzyme antibody, Pseudo interleukin-1 beta converting enzyme antibody, Pseudo interleukin-1beta converting enzyme antibody, PSEUDO-ICE antibody
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UniProt
- Q5EG05
抗原
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