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CAMK2B 抗体 (AA 1-300)

This anti-CAMK2B antibody is a 兔 多克隆 antibody detecting CAMK2B in ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7146447
发货至: 中国

Quick Overview for CAMK2B 抗体 (AA 1-300) (ABIN7146447)

抗原

See all CAMK2B 抗体
CAMK2B (Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B))

适用

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宿主

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克隆类型

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多克隆

标记

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This CAMK2B antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 1-300

    交叉反应

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human Calcium/calmodulin-dependent protein kinase type II subunit beta protein (1-300AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: IHC:1:20-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    CAMK2B (Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B))

    别名

    CAMK2B

    背景

    Background: Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca(2+) transport in skeletal muscle. In neurons, plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner. This structural function is required for correct targeting of CaMK2A, which acts downstream of NMDAR to promote dendritic spine and synapse formation and maintain synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning. In developing hippocampal neurons, promotes arborization of the dendritic tree and in mature neurons, promotes dendritic remodeling. Participates in the modulation of skeletal muscle function in response to exercise. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca(2+) transport and in fast-twitch muscle participates in the control of Ca(2+) release from the SR through phosphorylation of triadin, a ryanodine receptor-coupling factor, and phospholamban (PLN/PLB), an endogenous inhibitor of SERCA2A/ATP2A2.

    Aliases: Calcium/calmodulin dependent protein kinase (CaM kinase) II beta antibody, Calcium/calmodulin dependent protein kinase II beta antibody, Calcium/calmodulin dependent protein kinase IIB antibody, Calcium/calmodulin dependent protein kinase type II beta chain antibody, calcium/calmodulin-dependent protein kinase II beta antibody, Calcium/calmodulin-dependent protein kinase type II subunit beta antibody, CAM 2 antibody, CaM kinase II beta chain antibody, CaM kinase II beta subunit antibody, CaM kinase II subunit beta antibody, CaM-kinase II beta chain antibody, CAM2 antibody, CAMK 2 antibody, CAMK 2B antibody, CaMK II beta subunit antibody, CaMK II subunit beta antibody, CaMK-II subunit beta antibody, CAMK2 antibody, CaMK2 beta antibody, Camk2b antibody, CAMKB antibody, CaMKII beta subunit antibody, CaMKIIB antibody, KCC2B_HUMAN antibody, MGC29528 antibody, Proline rich calmodulin dependent protein kinase antibody, proline rich calmodulin-dependent protein kinase antibody

    UniProt

    Q13554

    途径

    WNT signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity
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