MST1R 抗体 (pTyr1238) (Biotin)
Quick Overview for MST1R 抗体 (pTyr1238) (Biotin) (ABIN710338)
抗原
See all MST1R 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr1238
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交叉反应
- 人, 猴, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human MST1R around the phosphorylation site of Tyr1238
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亚型
- IgG
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anti-Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R) (AA 89-275) antibody
MST1R 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R) (pTyr1238) antibodyMST1R 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R) (AA 1092-1316) antibodyMST1R 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R) (C-Term) antibodyMST1R 适用: 人, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R) (AA 210-320) antibodyMST1R 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B5A9 unconjugated
anti-Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R) (pTyr1238), (pTyr1239) antibodyMST1R 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R) (pSer1394) antibodyMST1R 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R) (N-Term) antibodyMST1R 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R) (AA 1175-1400) antibodyMST1R 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R) (AA 600-633) antibodyMST1R 适用: 人 WB 宿主: 兔 Polyclonal RB58004 unconjugated
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应用备注
- WB 1:300-5000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- MST1R (Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R))
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别名
- Ron
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背景
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Synonyms: RON, PTK8, CD136, CDw136, Macrophage-stimulating protein receptor, MSP receptor, Protein-tyrosine kinase 8, p185-Ron, MST1R
Background: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to MST1 ligand. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces autophosphorylation of RON on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1 or the adapter GAB1. Recruitment of these downstream effectors by RON leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. RON signaling activates the wound healing response by promoting epithelial cell migration, proliferation as well as survival at the wound site. Plays also a role in the innate immune response by regulating the migration and phagocytic activity of macrophages. Alternatively, RON can also promote signals such as cell migration and proliferation in response to growth factors other than MST1 ligand.
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基因ID
- 4486
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UniProt
- Q04912
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途径
- RTK signaling
抗原
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