GRK2 抗体 (AA 440-689)
Quick Overview for GRK2 抗体 (AA 440-689) (ABIN7145437)
抗原
See all GRK2 (ADRBK1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 440-689
-
交叉反应
- 人, 小鼠
-
纯化方法
- Antigen Affinity Purified
-
免疫原
- Recombinant Human Beta-adrenergic receptor kinase 1 protein (440-689AA)
-
亚型
- IgG
-
-
-
-
应用备注
- Recommended dilution: WB:1:200-1:1000,
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
-
别名
- GRK2
-
背景
-
Background: Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner.
Aliases: ADRBK1 antibody, Adrenergic beta receptor kinase 1 antibody, ARBK1_HUMAN antibody, BARK antibody, BARK1 antibody, Beta adrenergic receptor kinase 1 antibody, Beta ARK 1 antibody, Beta ARK1 antibody, Beta-adrenergic receptor kinase 1 antibody, Beta-ARK-1 antibody, FLJ16718 antibody, G protein coupled receptor kinase 2 antibody, G-protein coupled receptor kinase 2 antibody, GRK2 antibody
-
UniProt
- P25098
-
途径
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling
抗原
-