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ATG14 抗体 (AA 1-492) (FITC)

This anti-ATG14 antibody is a 兔 多克隆 antibody detecting ATG14 in . Suitable for 人.
产品编号 ABIN7145341
发货至: 中国

Quick Overview for ATG14 抗体 (AA 1-492) (FITC) (ABIN7145341)

抗原

See all ATG14 抗体
ATG14 (ATG14 Autophagy Related 14 (ATG14))

适用

  • 35
  • 7
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  • 1

宿主

  • 27
  • 8

克隆类型

  • 27
  • 8
多克隆

标记

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This ATG14 antibody is conjugated to FITC

应用范围

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  • 抗原表位

    • 7
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    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
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    AA 1-492

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Beclin 1-associated autophagy-related key regulator protein (1-492AA)

    亚型

    IgG
  • 限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    ATG14 (ATG14 Autophagy Related 14 (ATG14))

    别名

    ATG14

    背景

    Background: Required for both basal and inducible autophagy. Determines the localization of the autophagy-specific PI3-kinase complex PI3KC3-C1 (PubMed:18843052, PubMed:19050071). Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidylethanolamine (PubMed:19270696, PubMed:20713597). Promotes BECN1 translocation from the trans-Golgi network to autophagosomes (PubMed:20713597). Enhances PIK3C3 activity in a BECN1-dependent manner. Essential for the autophagy-dependent phosphorylation of BECN1 (PubMed:23878393). Stimulates the phosphorylation of BECN1, but suppresses the phosphorylation PIK3C3 by AMPK (PubMed:23878393). Binds to STX17-SNAP29 binary t-SNARE complex on autophagosomes and primes it for VAMP8 interaction to promote autophagosome-endolysosome fusion (PubMed:25686604). Modulates the hepatic lipid metabolism (By similarity).

    Aliases: 4832427M01 antibody, ATG14 antibody, Atg14L antibody, Autophagy-related protein 14-like protein antibody, BAKOR_HUMAN antibody, Barkor antibody, Beclin 1-associated autophagy-related key regulator antibody, D14Ertd114e antibody, D14Ertd436e antibody, KIAA0831 antibody, mCG_6911 antibody

    UniProt

    Q6ZNE5

    途径

    Autophagy
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