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ATG14 抗体 (AA 1-492) (Biotin)

ATG14 适用: 人 ELISA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN7145340
发货至: 中国
  • 抗原 See all ATG14 抗体
    ATG14 (ATG14 Autophagy Related 14 (ATG14))
    抗原表位
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-492
    适用
    • 46
    • 15
    • 8
    • 1
    宿主
    • 38
    • 8
    克隆类型
    • 38
    • 8
    多克隆
    标记
    • 19
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This ATG14 antibody is conjugated to Biotin
    应用范围
    • 27
    • 21
    • 17
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Beclin 1-associated autophagy-related key regulator protein (1-492AA)
    亚型
    IgG
    Top Product
    Discover our top product ATG14 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    ATG14 (ATG14 Autophagy Related 14 (ATG14))
    别名
    ATG14 (ATG14 产品)
    别名
    ATG14L antibody, BARKOR antibody, KIAA0831 antibody, 4832427M01 antibody, Atg14L antibody, D14Ertd114e antibody, D14Ertd436e antibody, RGD1304610 antibody, autophagy related 14 antibody, ATG14 antibody, Atg14 antibody
    背景

    Background: Required for both basal and inducible autophagy. Determines the localization of the autophagy-specific PI3-kinase complex PI3KC3-C1 (PubMed:18843052, PubMed:19050071). Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidylethanolamine (PubMed:19270696, PubMed:20713597). Promotes BECN1 translocation from the trans-Golgi network to autophagosomes (PubMed:20713597). Enhances PIK3C3 activity in a BECN1-dependent manner. Essential for the autophagy-dependent phosphorylation of BECN1 (PubMed:23878393). Stimulates the phosphorylation of BECN1, but suppresses the phosphorylation PIK3C3 by AMPK (PubMed:23878393). Binds to STX17-SNAP29 binary t-SNARE complex on autophagosomes and primes it for VAMP8 interaction to promote autophagosome-endolysosome fusion (PubMed:25686604). Modulates the hepatic lipid metabolism (By similarity).

    Aliases: 4832427M01 antibody, ATG14 antibody, Atg14L antibody, Autophagy-related protein 14-like protein antibody, BAKOR_HUMAN antibody, Barkor antibody, Beclin 1-associated autophagy-related key regulator antibody, D14Ertd114e antibody, D14Ertd436e antibody, KIAA0831 antibody, mCG_6911 antibody

    UniProt
    Q6ZNE5
    途径
    Autophagy
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