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BNIP3L/NIX 抗体 (AA 1-187)

This anti-BNIP3L/NIX antibody is a 兔 多克隆 antibody detecting BNIP3L/NIX in IHC 和 ELISA. Suitable for 人.
产品编号 ABIN7145332
发货至: 中国
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Quick Overview for BNIP3L/NIX 抗体 (AA 1-187) (ABIN7145332)

抗原

See all BNIP3L/NIX (BNIP3L) 抗体
BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))

适用

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宿主

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克隆类型

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多克隆

标记

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This BNIP3L/NIX antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA
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    AA 1-187

    原理

    BNIP3L Antibody

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like protein (1-187AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))

    别名

    BNIP3L

    背景

    Background: Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumor suppressor.

    Aliases: Adenovirus E1B19k binding protein B5 antibody, Adenovirus E1B19K-binding protein B5 antibody, BCL2/adenovirus E1B 19 kd protein interacting protein 3a antibody, BCL2/adenovirus E1B 19 kDa protein interacting protein 3A antibody, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like antibody, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A antibody, BCL2/adenovirus E1B 19 kDa interacting protein 3 like antibody, BNI3L_HUMAN antibody, BNIP3a antibody, BNIP3H antibody, BNIP3L antibody, BNIP3L protein antibody, NIP3 like protein X antibody, NIP3-like protein X antibody, NIP3L antibody, NIX antibody

    UniProt

    O60238

    途径

    Autophagy
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