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BBS5 抗体 (AA 224-317) (HRP)

This HRP-conjugated 兔 多克隆 anti-BBS5 antibody specifically detects BBS5 in ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7145245
发货至: 中国
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Quick Overview for BBS5 抗体 (AA 224-317) (HRP) (ABIN7145245)

抗原

See all BBS5 抗体
BBS5 (Bardet-Biedl Syndrome 5 (BBS5))

适用

  • 22
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  • 1
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宿主

  • 13
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克隆类型

  • 15
  • 8
多克隆

标记

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This BBS5 antibody is conjugated to HRP

应用范围

  • 15
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  • 5
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ELISA
  • 抗原表位

    • 6
    • 3
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    • 2
    • 1
    • 1
    • 1
    AA 224-317

    原理

    BBS5 Antibody, HRP conjugated

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Bardet-Biedl syndrome 5 protein (224-317AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    BBS5 (Bardet-Biedl Syndrome 5 (BBS5))

    别名

    BBS5

    背景

    Background: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for BBSome complex ciliary localization but not for the proper complex assembly.

    Aliases: Bardet Biedl syndrome 5 protein antibody, Bardet-Biedl syndrome 5 protein antibody, BBS5 antibody, BBS5_HUMAN antibody

    UniProt

    Q8N3I7

    途径

    Hedgehog Signaling
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