BIRC3 抗体 (AA 76-245) (Biotin)
Quick Overview for BIRC3 抗体 (AA 76-245) (Biotin) (ABIN7145204)
抗原
See all BIRC3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 76-245
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Baculoviral IAP repeat-containing protein 3 protein (76-245AA)
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亚型
- IgG
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anti-Baculoviral IAP Repeat Containing 3 (BIRC3) antibody
BIRC3 适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (AA 1-180) antibodyBIRC3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (AA 1-604) antibodyBIRC3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (AA 1-604) antibodyBIRC3 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (AA 59-88), (N-Term) antibodyBIRC3 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB34025 unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (AA 76-245) antibodyBIRC3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (Internal Region) antibodyVerified BIRC3 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (AA 255-529) antibodyBIRC3 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 1D12 unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (AA 101-131), (N-Term) antibodyBIRC3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB2213 unconjugated
anti-Baculoviral IAP Repeat Containing 3 (BIRC3) (AA 101-131) antibodyBIRC3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))
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别名
- BIRC3
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背景
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Background: Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non-canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins for its E3 ubiquitin-protein ligase activity include: RIPK1, RIPK2, RIPK3, RIPK4, CASP3, CASP7, CASP8, IKBKE, TRAF1, and BCL10. Acts as an important regulator of innate immune signaling via regulation of Toll-like receptors (TLRs), Nodlike receptors (NLRs) and RIG-I like receptors (RLRs), collectively referred to as pattern recognition receptors (PRRs). Protects cells from spontaneous formation of the ripoptosome, a large multi-protein complex that has the capability to kill cancer cells in a caspase-dependent and caspase-independent manner. Suppresses ripoptosome formation by ubiquitinating RIPK1 and CASP8.
Aliases: AIP 1 antibody, AIP1 antibody, API 2 antibody, API2 antibody, Apoptosis inhibitor 2 antibody, Baculoviral IAP repeat containing 3 antibody, Baculoviral IAP repeat containing protein 3 antibody, Baculoviral IAP repeat-containing protein 3 antibody, BIRC 3 antibody, BIRC3 antibody, BIRC3_HUMAN antibody, C IAP2 antibody, C-IAP2 antibody, Cellular inhibitor of apoptosis 2 antibody, cellular inhibitor of apoptosis protein 2 antibody, CIAP 2 antibody, CIAP2 antibody, HAIP 1 antibody, HAIP1 antibody, HIAP 1 antibody, HIAP-1 antibody, HIAP1 antibody, IAP homolog C antibody, IAP-1 antibody, Inhibitor of apoptosis protein 1 antibody, MALT 2 antibody, MALT2 antibody, Mammalian IAP homolog C antibody, MIHC antibody, RING finger protein 49 antibody, RNF49 antibody, TNFR2 TRAF signaling complex protein 1 antibody, TNFR2 TRAF signalling complex protein antibody, TNFR2-TRAF-signaling complex protein 1 antibody
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UniProt
- Q13489
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途径
- Apoptosis, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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