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- 抗原 See all Axin (AXIN1) 抗体
- Axin (AXIN1) (Axin 1 (AXIN1))
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抗原表位
- AA 418-707
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Axin antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Axin-1 protein (418-707AA)
- 亚型
- IgG
- Top Product
- Discover our top product AXIN1 Primary Antibody
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anti-Axin 1 (AXIN1) (AA 546-752) antibody
AXIN1 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 4E9F1 unconjugated
anti-Axin 1 (AXIN1) (AA 618-827) antibodyAXIN1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Axin 1 (AXIN1) (AA 643-740) antibodyAXIN1 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 2B11 unconjugated
anti-Axin 1 (AXIN1) (AA 470-570) antibody (Atto 488)AXIN1 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal Atto 488
anti-Axin 1 (AXIN1) (AA 470-570) antibody (Atto 594)AXIN1 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal Atto 594
anti-Axin 1 (AXIN1) (AA 470-570) antibody (Atto 390)AXIN1 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal Atto 390
anti-Axin 1 (AXIN1) (AA 470-570) antibody (FITC)AXIN1 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal FITC
anti-Axin 1 (AXIN1) (AA 546-752) antibodyAXIN1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4F10G1 unconjugated
anti-Axin 1 (AXIN1) (AA 653-862) antibodyAXIN1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Axin 1 (AXIN1) (AA 710-738) antibodyAXIN1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- Axin (AXIN1) (Axin 1 (AXIN1))
- 别名
- AXIN1 (AXIN1 产品)
- 背景
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Background: Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects, down-regulates CTNNB1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway. In Wnt signaling, probably facilitates the phosphorylation of CTNNB1 and APC by GSK3B. Likely to function as a tumor suppressor. Facilitates the phosphorylation of TP53 by HIPK2 upon ultraviolet irradiation. Enhances TGF-beta signaling by recruiting the RNF111 E3 ubiquitin ligase and promoting the degradation of inhibitory SMAD7. Also component of the AXIN1-HIPK2-TP53 complex which controls cell growth, apoptosis and development.
Aliases: AI316800 antibody, AXIN antibody, Axin 1 antibody, Axin-1 antibody, axin1 antibody, AXIN1_HUMAN antibody, Axis inhibition protein 1 antibody, Axis Inhibitor 1 antibody, Fu antibody, fused antibody, Fused, mouse, homolog of antibody, hAxin antibody, Kb antibody, Ki antibody, kinky antibody, knobbly antibody, MGC132911 antibody, MGC52315 antibody, PPP1R49 antibody, Protein Fused antibody, Protein phosphatase 1 regulatory subunit 49 antibody
- UniProt
- O15169
- 途径
- WNT signaling, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling
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