FZD7 抗体 (AA 501-574) (HRP)
Quick Overview for FZD7 抗体 (AA 501-574) (HRP) (ABIN710060)
抗原
See all FZD7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 501-574
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Pig,Chicken,Guinea Pig
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Frizzled 7
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亚型
- IgG
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- FZD7 (Frizzled Family Receptor 7 (FZD7))
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别名
- Frizzled 7
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背景
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Synonyms: FzE3, Frizzled-7, Fz-7, hFz7, FZD7
Background: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
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基因ID
- 8324
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UniProt
- O75084
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途径
- WNT signaling, Stem Cell Maintenance
抗原
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