OAS1 抗体 (AA 296-395)
Quick Overview for OAS1 抗体 (AA 296-395) (ABIN7142170)
抗原
See all OAS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 296-395
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human 2\'-5\'-oligoadenylate synthase 1 protein (296-395AA)
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亚型
- IgG
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anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 74-165) antibody
OAS1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 139-358) antibodyOAS1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 302-330), (C-Term) antibodyOAS1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB1937 unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (Middle Region) antibodyOAS1 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 马, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 74-165) antibodyOAS1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C5 unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (C-Term) antibodyOAS1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 324-373) antibodyOAS1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 1-364) antibodyOAS1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 1-400) antibodyOAS1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (N-Term) antibodyOAS1 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))
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别名
- OAS1
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背景
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Background: Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes higher oligomers of 2\'-5\'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L. The secreted form displays antiviral effect against vesicular stomatitis virus (VSV), herpes simplex virus type 2 (HSV-2), and encephalomyocarditis virus (EMCV) and stimulates the alternative antiviral pathway independent of RNase L.
Aliases: (2 5')oligo(A) synthetase 1 antibody, (2-5'')oligo(A) synthase 1 antibody, 2 5 Oligoadenylate Synthetase 1 antibody, 2 5' oligo A synthase 1 antibody, 2 5' oligo A synthetase 1 antibody, 2 5A synthase 1 antibody, 2 5A synthetase 1 antibody, 2' 5' oligo A synthetase 1 antibody, 2' 5' oligoadenylate synthetase 1 40/46 kDa antibody, 2' 5' oligoadenylate synthetase 1 antibody, 2' 5' oligoisoadenylate synthetase 1 antibody, 2''-5''-oligoadenylate synthase 1 antibody, 2'5' oligo A synthetase 1 antibody, 2'5' oligoadenylate synthetase 1 antibody, 2'5' oligoisoadenylate synthetase 1 antibody, 2-5A synthase 1 antibody, E18/E16 antibody, IFI 4 antibody, IFI4 antibody, OAS 1 antibody, OAS1 antibody, OAS1_HUMAN antibody, OIAS antibody, OIASI antibody, p46/p42 OAS antibody
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UniProt
- P00973
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途径
- Hepatitis C
抗原
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