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PDK3 抗体 (AA 137-406)

This anti-PDK3 antibody is a 兔 多克隆 antibody detecting PDK3 in WB, ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7142007
发货至: 中国

Quick Overview for PDK3 抗体 (AA 137-406) (ABIN7142007)

抗原

See all PDK3 抗体
PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))

适用

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宿主

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克隆类型

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多克隆

标记

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This PDK3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
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    AA 137-406

    交叉反应

    人, 小鼠

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial protein (137-406AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))

    别名

    PDK3

    背景

    Background: Inhibits pyruvate dehydrogenase activity by phosphorylation of the E1 subunit PDHA1, and thereby regulates glucose metabolism and aerobic respiration. Can also phosphorylate PDHA2. Decreases glucose utilization and increases fat metabolism in response to prolonged fasting, and as adaptation to a high-fat diet. Plays a role in glucose homeostasis and in maintaining normal blood glucose levels in function of nutrient levels and under starvation. Plays a role in the generation of reactive oxygen species.

    Aliases: [Pyruvate dehydrogenase [lipoamide] kinase isozyme 3 mitochondrial antibody, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3 antibody, CMTX6 antibody, GS1-358P8.4 antibody, mitochondrial antibody, PDK3 antibody, PDK3_HUMAN antibody, Pyruvate dehydrogenase kinase isoenzyme 3 antibody, Pyruvate dehydrogenase kinase isoform 3 antibody, Pyruvate dehydrogenase kinase isozyme 3 antibody, Pyruvate dehydrogenase lipoamide kinase isozyme 3 mitochondrial antibody

    UniProt

    Q15120

    途径

    PI3K-Akt Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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