FEN1 抗体 (AA 85-383) (Biotin)
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北京 101111
Quick Overview for FEN1 抗体 (AA 85-383) (Biotin) (ABIN7140479)
抗原
See all FEN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 85-383
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原理
- FEN1 Antibody, Biotin conjugated
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交叉反应
- Arabidopsis thaliana
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纯化方法
- Protein G purified
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纯度
- >95 %
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免疫原
- Recombinant Arabidopsis thaliana Flap endonuclease 1 protein (85-383AA)
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亚型
- IgG
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anti-Flap Structure-Specific Endonuclease 1 (FEN1) (AA 50-380) antibody
FEN1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Flap Structure-Specific Endonuclease 1 (FEN1) antibodyFEN1 适用: 人 WB, IHC, IF, IP, IHC (p), ICC, PLA 宿主: 兔 Polyclonal unconjugated
anti-Flap Structure-Specific Endonuclease 1 (FEN1) antibodyFEN1 适用: 人, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Flap Structure-Specific Endonuclease 1 (FEN1) antibodyFEN1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Monoclonal 4D9 unconjugated Recombinant Antibody
anti-Flap Structure-Specific Endonuclease 1 (FEN1) (AA 1-380) antibodyFEN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Flap Structure-Specific Endonuclease 1 (FEN1) antibodyFEN1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Flap Structure-Specific Endonuclease 1 (FEN1) (Internal Region) antibodyFEN1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Flap Structure-Specific Endonuclease 1 (FEN1) antibodyFEN1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Flap Structure-Specific Endonuclease 1 (FEN1) antibodyFEN1 适用: 人, 小鼠 WB, ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Flap Structure-Specific Endonuclease 1 (FEN1) antibodyFEN1 适用: 人, 小鼠 WB, IP 宿主: 小鼠 Monoclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- FEN1 (Flap Structure-Specific Endonuclease 1 (FEN1))
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别名
- FEN1
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背景
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Background: Structure-specific nuclease with 5\'-flap endonuclease and 5\'-3\' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5\'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5\'-end of a downstream Okazaki fragment. It enters the flap from the 5\'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinicapyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5\'-3\' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
Aliases: FEN1 antibody, At5g26680 antibody, F21E10.3Flap endonuclease 1 antibody, FEN-1 antibody, EC 3.1.-.- antibody, Flap structure-specific endonuclease 1 antibody
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UniProt
- O65251
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途径
- Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA
抗原
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