FEN1 抗体 (AA 85-383)
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- 抗原 See all FEN1 抗体
- FEN1 (Flap Structure-Specific Endonuclease 1 (FEN1))
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抗原表位
- AA 85-383
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适用
- Arabidopsis thaliana
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FEN1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- Arabidopsis thaliana
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Arabidopsis thaliana Flap endonuclease 1 protein (85-383AA)
- 亚型
- IgG
- Top Product
- Discover our top product FEN1 Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:1000-1:5000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- FEN1 (Flap Structure-Specific Endonuclease 1 (FEN1))
- 别名
- FEN1 (FEN1 产品)
- 背景
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Background: Structure-specific nuclease with 5\'-flap endonuclease and 5\'-3\' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5\'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5\'-end of a downstream Okazaki fragment. It enters the flap from the 5\'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinicapyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5\'-3\' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
Aliases: FEN1 antibody, At5g26680 antibody, F21E10.3Flap endonuclease 1 antibody, FEN-1 antibody, EC 3.1.-.- antibody, Flap structure-specific endonuclease 1 antibody
- UniProt
- O65251
- 途径
- Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA
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