GRK2 抗体 (C-Term)
Quick Overview for GRK2 抗体 (C-Term) (ABIN7140291)
抗原
See all GRK2 (ADRBK1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应
- 犬, 人, 小鼠, Pig, 大鼠
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纯化方法
- Affinity purified
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免疫原
- Purified recombinant human ADRBK1(C-term.) protein fragments expressed in E.coli.
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亚型
- IgG1, IgG1 kappa
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应用备注
- Recommended dilution:WB:1:500-1:5000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine ( pH 7.4, 150 mM NaCl) with 0.2 % sodium azide, 50 %,glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
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别名
- ADRBK1
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背景
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Background: The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1.
Aliases: GRK2, BARK1, BETA-ARK1
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UniProt
- P25098
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途径
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling
抗原
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