PEN2 抗体 (AA 39-57)
Quick Overview for PEN2 抗体 (AA 39-57) (ABIN7139851)
抗原
See all PEN2 (PSENEN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 39-57
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Peptide sequence from Human Gamma-secretase subunit PEN-2 protein (39-57AA)
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亚型
- IgG
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anti-Presenilin Enhancer 2 Homolog (PSENEN) (AA 6-80) antibody
PSENEN 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Presenilin Enhancer 2 Homolog (PSENEN) (AA 1-101) antibodyPSENEN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C12-G5 unconjugated
anti-Presenilin Enhancer 2 Homolog (PSENEN) (AA 1-50) antibodyPSENEN 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, Opossum WB 宿主: 兔 Polyclonal unconjugated
anti-Presenilin Enhancer 2 Homolog (PSENEN) (AA 20-69) antibodyPSENEN 适用: 人, 小鼠, 犬, 马, 豚鼠, 兔, 猴, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Presenilin Enhancer 2 Homolog (PSENEN) (C-Term) antibodyPSENEN 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠, 兔, 斑马鱼, 猴, Bat, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Presenilin Enhancer 2 Homolog (PSENEN) (C-Term) antibodyPSENEN 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Presenilin Enhancer 2 Homolog (PSENEN) (N-Term) antibodyPSENEN 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Presenilin Enhancer 2 Homolog (PSENEN) (C-Term) antibodyPSENEN 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:200-1:500,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))
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别名
- PSENEN
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背景
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Background: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein) (PubMed:12522139, PubMed:12763021, PubMed:12740439, PubMed:12679784, PubMed:24941111). The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels (Probable). PSENEN modulates both endoproteolysis of presenilin and gamma-secretase activity (PubMed:12522139, PubMed:12763021, PubMed:12740439, PubMed:12679784, PubMed:24941111).
Aliases: Gamma secretase subunit PEN 2 antibody, Gamma Secretase Subunit PEN2 antibody, Gamma-secretase subunit PEN-2 antibody, Hematopoietic stem/progenitor cells protein MDS033 antibody, MDS033 antibody, MSTP064 antibody, PEN 2 antibody, PEN2_HUMAN antibody, Presenilin Enhancer 2 antibody, Presenilin enhancer 2 homolog antibody, Presenilin enhancer protein 2 antibody, PSEN2 antibody, psenen antibody
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UniProt
- Q9NZ42
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途径
- Notch Signaling, Neurotrophin Signaling Pathway
抗原
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