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SHP1 抗体 (pTyr536)

This anti-SHP1 antibody is a 兔 多克隆 antibody detecting SHP1 in ELISA, IHC 和 IF. Suitable for 人.
产品编号 ABIN7139023
发货至: 中国

Quick Overview for SHP1 抗体 (pTyr536) (ABIN7139023)

抗原

See all SHP1 (PTPN6) 抗体
SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))

适用

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宿主

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克隆类型

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多克隆

标记

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This SHP1 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    pTyr536

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of tyrosine 536 (S-E-Y(p)-G-N) derived from Human SHP-1.

    亚型

    IgG
  • 应用备注

    IHC:1:50-1:100, IF:1:100-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))

    别名

    PTPN6

    背景

    Background: Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus.

    Migone TS, et al. (1998) Proc Natl Acad Sci USA, 95(7): 3845-3850.
    Timms JF, et al.(1998) Mol Cell Biol, 18(7): 3838-3850.
    Kanagasundaram V, et al. (1999) Mol Cell Biol, 19(6): 4079-4092.
    Hauck CR, et al. (1999) Infect Immun, 67(10): 5490-5494.

    Aliases: 70Z-SHP antibody, EC 3.1.3.48 antibody, HCP antibody, HCPH antibody, Hematopoietic cell phosphatase antibody, Hematopoietic cell protein tyrosine phosphatase antibody, Hematopoietic cell protein-tyrosine phosphatase antibody, HPTP1C antibody, Protein tyrosine phosphatase 1C antibody, Protein tyrosine phosphatase non receptor type 6 antibody, Protein tyrosine phosphatase SHP1 antibody, Protein-tyrosine phosphatase 1C antibody, protein-tyrosine phosphatase SHP 1 antibody, Protein-tyrosine phosphatase SHP-1 antibody, PTN6_HUMAN antibody, PTP 1C antibody, PTP-1C antibody, PTP1C antibody, Ptpn6 antibody, SH PTP 1 antibody, SH PTP1 antibody, SH-PTP1 antibody, SHP 1 antibody, SHP 1L antibody, SHP1 antibody, SHP1L antibody, tyrosine protein phosphatase non receptor type 6 antibody, Tyrosine-protein phosphatase non-receptor type 6 antibody

    UniProt

    P29350

    途径

    JAK/STAT Signaling, TCR Signaling, TLR signaling, Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, BCR Signaling
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