ITCH 抗体 (pTyr420)
Quick Overview for ITCH 抗体 (pTyr420) (ABIN7139004)
抗原
See all ITCH 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr420
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交叉反应
- 人, 小鼠
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纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
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免疫原
- Peptide sequence around phosphorylation site of tyrosine 420(F-I-Y(p)-G-N) derived from Human ITCH .
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亚型
- IgG
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anti-Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH) (Internal Region) antibody
Verified ITCH 适用: 人 ELISA, WB, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH) antibodyKO Validated ITCH 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH) (Tyr420) antibodyITCH 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH) (AA 29-303) antibodyITCH 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH) (AA 92-190) antibodyITCH 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 1B8 unconjugated
anti-Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH) (AA 50-150) antibodyKO Validated ITCH 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH) antibodyITCH 适用: 人 ELISA, WB 宿主: 兔 Monoclonal 9C3 unconjugated Recombinant Antibody
anti-Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH) (AA 143-192) antibodyITCH 适用: 人, Cow, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH) (AA 410-437), (Middle Region) antibodyITCH 适用: 人, 小鼠, 大鼠, 猴 WB, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC:1:50-1:100,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- ITCH (Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH))
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别名
- ITCH
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背景
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Background:
Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. The protein encoded by this gene interacts with atrophin-1. This encoded protein is a closely related member of the NEDD4-like protein family. This family of proteins are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. This encoded protein contains four tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain.
Chen X., Genomics 73:238-241(2001).
Deloukas P., Nature 414:865-871(2001).
Wood J.D., Mol. Cell. Neurosci. 11:149-160(1998).Aliases: ADMFD antibody, AIF4 antibody, AIP4 antibody, Atrophin 1 interacting protein 4 antibody, Atrophin-1-interacting protein 4 antibody, dJ468O1.1 antibody, dJ468O1.1 (atrophin 1 interacting protein 4 (AIP4)) antibody, dJ468O1.1 atrophin 1 interacting protein 4 AIP4 antibody, E3 ubiquitin protein ligase Itchy homolog antibody, E3 ubiquitin-protein ligase Itchy homolog antibody, EC 6.3.2 antibody, Itch antibody, ITCH_HUMAN antibody, Itchy E3 ubiquitin protein ligase antibody, Itchy E3 ubiquitin protein ligase homolog antibody, Itchy E3 ubiquitin protein ligase homolog mouse antibody, Itchy E3 ubiquitin protein ligase, mouse, homolog of antibody, Itchy homolog E3 ubiquitin protein ligase antibody, Itchy mouse homolog E3 ubiquitin protein ligase antibody, NAPP1 antibody, NFE2 associated polypeptide 1 antibody, NFE2-associated polypeptide 1 antibody, Ubiquitin protein ligase ITCH antibody
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UniProt
- Q96J02
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途径
- Activation of Innate immune Response, CXCR4-mediated Signaling Events
抗原
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