Ephrin B2 抗体 (pTyr330)
Quick Overview for Ephrin B2 抗体 (pTyr330) (ABIN7138984)
抗原
See all Ephrin B2 (EFNB2) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pTyr330
-
交叉反应
- 人, 小鼠
-
纯化方法
- Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
-
免疫原
- Peptide sequence around phosphorylation site of tyrosine 330 (N-I-Y(p)-Y-K) derived from Human Ephrin-B2
-
亚型
- IgG
-
-
-
-
应用备注
- WB:1:500-1:1000,
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- Ephrin B2 (EFNB2)
-
别名
- EFNB2
-
背景
-
Background: Adducins are a family of cytoskeleton proteins encoded by three genes (a, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. a- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. a- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms, however, not all variants have been fully described.
Chrencik JE,et al.( 2006) J Biol Chem,281(38):28185-28192.
Kertesz N, et al. (2006) Blood, 107(6):2330-2338.
Noren NK, et al. (2004) Proc Natl Acad Sci USA, 101(15):5583-5588.Aliases: EFN B2 antibody, EFNB 2 antibody, Efnb2 antibody, EFNB2_HUMAN antibody, Eph related receptor tyrosine kinase ligand 5 antibody, EPH-related receptor tyrosine kinase ligand 5 antibody, ephrin B2 antibody, Ephrin-B2 antibody, EphrinB2 antibody, EPLG 5 antibody, EPLG5 antibody, Htk L antibody, HTK ligand antibody, HTK-L antibody, HTKL antibody, LERK 5 antibody, LERK-5 antibody, LERK5 antibody, Ligand of eph related kinase 5 antibody, MGC126226 antibody, MGC126227 antibody, MGC126228 antibody, OTTMUSP00000024973 antibody
-
UniProt
- P52799
-
途径
- RTK signaling, Regulation of Muscle Cell Differentiation
抗原
-