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产品编号 ABIN6261455
发货至: 中国
  • 抗原 See all Ephrin B2 (EFNB2) 抗体
    Ephrin B2 (EFNB2)
    抗原表位
    • 10
    • 9
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 57
    • 34
    • 28
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 52
    • 4
    • 1
    克隆类型
    • 44
    • 12
    多克隆
    标记
    • 34
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    This Ephrin B2 antibody is un-conjugated
    应用范围
    • 34
    • 19
    • 13
    • 7
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    Ephrin B2 Antibody detects endogenous levels of total Ephrin B2.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human Ephrin B2, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    Ephrin B2 (EFNB2)
    别名
    EFNB2 (EFNB2 产品)
    别名
    EFNB2 antibody, efnb2 antibody, ephrin-B2 antibody, htkl antibody, eplg5 antibody, htk-l antibody, lerk5 antibody, ephrinB2 antibody, efnb2a antibody, MGC68890 antibody, efnb2b antibody, ELF-2 antibody, Epl5 antibody, Eplg5 antibody, Htk-L antibody, LERK-5 antibody, Lerk5 antibody, NLERK-1 antibody, EPLG5 antibody, HTKL antibody, LERK5 antibody, ephrin B2 antibody, ephrin-B2 precursor antibody, ephrin B2 L homeolog antibody, ephrin B2 S homeolog antibody, EFNB2 antibody, efnb2 antibody, efnb2.L antibody, efnb2.S antibody, Efnb2 antibody
    背景

    Description: Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons.

    Gene: EFNB2

    分子量
    36kDa
    基因ID
    1948
    UniProt
    P52799
    途径
    RTK signaling, Regulation of Muscle Cell Differentiation
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