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SYK 抗体 (pTyr323)

This anti-SYK antibody is a 兔 多克隆 antibody detecting SYK in WB, IHC, ELISA 和 IF. Suitable for 人.
产品编号 ABIN7138980
发货至: 中国

Quick Overview for SYK 抗体 (pTyr323) (ABIN7138980)

抗原

See all SYK 抗体
SYK (Spleen tyrosine Kinase (SYK))

适用

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宿主

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克隆类型

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多克隆

标记

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This SYK antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
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    pTyr323

    交叉反应

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of tyrosine 323 (N-P-Y(p)-E- P) derived from Human syk.

    亚型

    IgG
  • 应用备注

    WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    SYK (Spleen tyrosine Kinase (SYK))

    别名

    SYK

    背景

    Background: Positive effector of BCR-stimulated responses. Couples the B-cell antigen receptor (BCR) to the mobilization of calcium ion either through a phosphoinositide 3-kinase-dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C-gamma-dependent pathway, when phosphorylated on Tyr-348 and Tyr-352. Thus the differential phosphorylation of Syk can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ion

    Zhang, J. et al. (2000) J. Biol. Chem. 275, 35442-35447.
    Turner, M. et al. (2000) Immunol. Today 21, 148-154.
    Decker, M. et al. (1998) J. Biol. Chem. 273, 8867-8874.
    Law, C.L. et al. (1996) Mol. Cell. Biol. 16, 1305-1315.

    Aliases: EC 2.7.10.2 antibody, kinase Syk antibody, KSYK antibody, KSYK_HUMAN antibody, p72-Syk antibody, p72syk antibody, Spleen tyrosine kinase antibody, Syk antibody, Tyrosine protein kinase SYK antibody, Tyrosine-protein kinase SYK antibody

    UniProt

    P43405

    途径

    Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling
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