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FLT1 抗体 (pTyr1213)

This 兔 多克隆 anti-FLT1 antibody specifically detects FLT1 in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7138921
发货至: 中国
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Quick Overview for FLT1 抗体 (pTyr1213) (ABIN7138921)

抗原

See all FLT1 抗体
FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

适用

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宿主

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克隆类型

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多克隆

标记

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This FLT1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
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    pTyr1213

    原理

    Phospho-FLT1 (Tyr1213) Antibody

    交叉反应

    小鼠, 大鼠

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of Tyrosine 1213(V-R-Y(p)-V-N) derived from Human VEGFR1.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))

    别名

    FLT1

    背景

    Background:

    Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform SFlt1 may have an inhibitory role in angiogenesis.

    Raghu H, et al. (2012) Mol Oncol 6, 33-47
    Ito N, Huang K, Claesson-Welsh L (2001) Cell Signal 13, 849-54
    Ito N, Wernstedt C, Engstr?m U, Claesson-Welsh L (1998) J Biol Chem 273, 23410-8

    Aliases: EC 2.7.10.1 antibody, FLT 1 antibody, FLT antibody, Flt-1 antibody, FLT1 antibody, Fms like tyrosine kinase 1 antibody, Fms related tyrosine kinase 1 antibody, Fms related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) antibody, Fms related tyrosine kinase 1 vascular endothelial growth factor/vascular permeability factor receptor antibody, Fms-like tyrosine kinase 1 antibody, FRT antibody, Soluble VEGF receptor 1 14 antibody, Soluble VEGFR1 variant 2 antibody, Soluble VEGFR1 variant 21 antibody, Tyrosine protein kinase FRT antibody, Tyrosine protein kinase receptor FLT antibody, Tyrosine-protein kinase FRT antibody, Tyrosine-protein kinase receptor FLT antibody, Vascular endothelial growth factor receptor 1 antibody, Vascular endothelial growth factor vascular permeability factor receptor antibody, Vascular permeability factor receptor 1 antibody, Vascular permeability factor receptor antibody, VEGFR 1 antibody, VEGFR-1 antibody, VEGFR1 antibody, VGFR1_HUMAN antibody

    UniProt

    P17948

    途径

    RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
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