APP 抗体 (pThr743)
Quick Overview for APP 抗体 (pThr743) (ABIN7138900)
抗原
See all APP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr743
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
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免疫原
- Peptide sequence around phosphorylation site of threonine743 /668 (A-V-T(p)-P-E) derived from Human Amyloid beta A4.
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亚型
- IgG
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anti-Amyloid beta (A4) Precursor Protein (APP) (C-Term) antibody
APP 适用: 人 WB, IF, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein (APP) antibodyAPP 适用: 人, 小鼠 WB, ELISA, IHC, IF, FM 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein (APP) (AA 666-670) antibodyAPP 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein (APP) (AA 18-270) antibodyAPP 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein (APP) (C-Term) antibodyAPP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein (APP) antibodyKO Validated APP 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein (APP) (AA 381-480) antibodyAPP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein (APP) (pThr668) antibodyAPP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein (APP) antibodyAPP 适用: 人 WB, ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Amyloid beta (A4) Precursor Protein (APP) (C-Term) antibodyAPP 适用: 人, 小鼠, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- APP (Amyloid beta (A4) Precursor Protein (APP))
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别名
- APP
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背景
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Background: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity By similarity. Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Ming-Sum Lee J. Cell Biol., Oct 2003, 163: 83.Tadashi Nakaya and Toshiharu Suzuki Genes Cells, Jun 2006, 11: 633 - 645Keun-A Chang, Mol. Cell. Biol., Jun 2006, 26: 4327 ?C 4338.Thor D. Stein J. Neurosci., Sep 2004, 24: 7707 - 7717
Aliases: A4 antibody, A4_HUMAN antibody, AAA antibody, ABETA antibody, ABPP antibody, AICD-50 antibody, AICD-57 antibody, AICD-59 antibody, AID(50) antibody, AID(57) antibody, AID(59) antibody, Alzheimer disease amyloid protein antibody, Amyloid intracellular domain 50 antibody, Amyloid intracellular domain 57 antibody, Amyloid intracellular domain 59 antibody, APP antibody, APPI antibody, Beta amyloid protein 42 antibody, Beta APP42 antibody, Beta-APP40 antibody, Beta-APP42 antibody, C31 antibody, Cerebral vascular amyloid peptide antibody, CVAP antibody, Gamma-CTF(50) antibody, Gamma-CTF(57) antibody, Gamma-CTF(59) antibody, PN-II antibody, PreA4 antibody, Protease nexin-II antibody, S-APP-alpha antibody, S-APP-beta antibody
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UniProt
- P05067
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途径
- Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour
抗原
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