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Topoisomerase II alpha 抗体 (pThr1343)

This anti-Topoisomerase II alpha antibody is a 兔 多克隆 antibody detecting Topoisomerase II alpha in WB 和 ELISA. Suitable for 人.
产品编号 ABIN7138889
发货至: 中国

Quick Overview for Topoisomerase II alpha 抗体 (pThr1343) (ABIN7138889)

抗原

See all Topoisomerase II alpha (TOP2A) 抗体
Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))

适用

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宿主

  • 103
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克隆类型

  • 90
  • 53
多克隆

标记

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This Topoisomerase II alpha antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    pThr1343

    交叉反应

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of threonine1343(E-K-T(p)-D-D) derived from Human TOP2A.

    亚型

    IgG
  • 应用备注

    WB:1:500-1:1000,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))

    别名

    TOP2A

    背景

    Background:

    This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event.

    Tsai-Pflugfelder M., Proc. Natl. Acad. Sci. U.S.A. 85:7177-7181(1988).
    Wasserman R.A., Cancer Res. 53:3591-3596(1993).
    Lang A.J., Gene 221:255-266(1998).

    Aliases: alpha isozyme antibody, ATP hydrolyzing DNA topoisomerase II alfa antibody, DNA gyrase antibody, DNA topoisomerase (ATP hydrolyzing) antibody, DNA topoisomerase 2 alpha antibody, DNA topoisomerase 2-alpha antibody, DNA topoisomerase II 170 kD antibody, DNA topoisomerase II alpha isozyme antibody, DNA topoisomerase II antibody, DNA Topoisomerase2 antibody, TOP 2A antibody, TOP2 antibody, TOP2A antibody, TOP2A_HUMAN antibody, Topoisomerase DNA II alpha 170 kDa antibody, TP2A antibody

    UniProt

    P11388

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases
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