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LIM Domain Kinase 1 抗体 (pThr508)

This anti-LIM Domain Kinase 1 antibody is a 兔 多克隆 antibody detecting LIM Domain Kinase 1 in WB, ELISA, IHC 和 IF. Suitable for 人.
产品编号 ABIN7138862
发货至: 中国

Quick Overview for LIM Domain Kinase 1 抗体 (pThr508) (ABIN7138862)

抗原

See all LIM Domain Kinase 1 (LIMK1) 抗体
LIM Domain Kinase 1 (LIMK1)

适用

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宿主

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克隆类型

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多克隆

标记

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This LIM Domain Kinase 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    pThr508

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of threonine 508 (R-Y-T(p)-V-V) derived from Human LIMK1.

    亚型

    IgG
  • 应用备注

    WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    LIM Domain Kinase 1 (LIMK1)

    别名

    LIMK1

    背景

    Background: Protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. Isoform 3 has a dominant negative effect on actin cytoskeletal changes. May be involved in brain development.

    Soosairajah J, et al. (2005) EMBO J.
    Ohashi K, et al. (2000) J Biol Chem, 275(5): 3577-82.
    Edwards DC, et al. (1999) Nat Cell Biol, 1(5): 253-9.

    Aliases: EC 2.7.11.1 antibody, LIM domain kinase 1 antibody, LIM motif-containing protein kinase antibody, LIMK antibody, LIMK-1 antibody, limk1 antibody, LIMK1_HUMAN antibody

    UniProt

    P53667

    途径

    Caspase Cascade in Apoptosis, Regulation of Cell Size, CXCR4-mediated Signaling Events
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