CAMK2D 抗体 (pThr287)
Quick Overview for CAMK2D 抗体 (pThr287) (ABIN7138827)
抗原
See all CAMK2D 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr287
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
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免疫原
- Peptide sequence around phosphorylation site of Threonine 287(Q-E-T(p)-V-E) derived from Human CaMK2- beta/ gamma/ delta.
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亚型
- IgG
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anti-Calcium/calmodulin-Dependent Protein Kinase II delta (CAMK2D) antibody
KO Validated CAMK2D 适用: 人 WB, IF, IHC (p), ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II delta (CAMK2D) (AA 301-410) antibodyCAMK2D 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 1A8 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II delta (CAMK2D) (Internal Region) antibodyCAMK2D 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II delta (CAMK2D) antibodyCAMK2D 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II delta (CAMK2D) (AA 221-250) antibodyCAMK2D 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB34171 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II delta (CAMK2D) (AA 1-260) antibodyCAMK2D 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II delta (CAMK2D) (AA 301-410) antibodyCAMK2D 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II delta (CAMK2D) (AA 301-410) antibodyCAMK2D 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2E1 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II delta (CAMK2D) (AA 448-478), (C-Term) antibodyCAMK2D 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB1259 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase II delta (CAMK2D) (C-Term) antibodyCAMK2D 适用: 人, 灵长类 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB:1:500-1:1000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CAMK2D (Calcium/calmodulin-Dependent Protein Kinase II delta (CAMK2D))
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别名
- CAMK2B/CAMK2G/CAMK2D
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背景
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Background: Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca2+ transport in skeletal muscle. In neurons, plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner. This structural function is required for correct targeting of CaMK2A, which acts downstream of NMDAR to promote dendritic spine and synapse formation and maintain synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning. In developing hippocampal neurons, promotes arborization of the dendritic tree and in mature neurons, promotes dendritic remodeling. Participates in the modulation of skeletal muscle function in response to exercise. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca2+ transport and in fast-twitch muscle participates in the control of Ca2+ release from the SR through phosphorylation of triadin, a ryanodine receptor-coupling factor, and phospholamban (PLN/PLB), an endogenous inhibitor of SERCA2A/ATP2A2.
Aliases: Calcium/calmodulin dependent protein kinase (CaM kinase) II beta antibody, Calcium/calmodulin dependent protein kinase II beta antibody, Calcium/calmodulin dependent protein kinase IIB antibody, Calcium/calmodulin dependent protein kinase type II beta chain antibody, calcium/calmodulin-dependent protein kinase II beta antibody, Calcium/calmodulin-dependent protein kinase type II subunit beta antibody, CAM 2 antibody, CaM kinase II beta chain antibody, CaM kinase II beta subunit antibody, CaM kinase II subunit beta antibody, CaM-kinase II beta chain antibody, CAM2 antibody, CAMK 2 antibody, CAMK 2B antibody, CaMK II beta subunit antibody, CaMK II subunit beta antibody, CaMK-II subunit beta antibody, CAMK2 antibody, CaMK2 beta antibody, Camk2b antibody, CAMKB antibody, CaMKII beta subunit antibody, CaMKIIB antibody, KCC2B_HUMAN antibody, MGC29528 antibody, Proline rich calmodulin dependent protein kinase antibody, proline rich calmodulin-dependent protein kinase antibody
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UniProt
- Q13554
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途径
- WNT signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction, Smooth Muscle Cell Migration
抗原
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