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RPA2 抗体 (pThr21)

This 兔 多克隆 anti-RPA2 antibody specifically detects RPA2 in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7138802
发货至: 中国
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Quick Overview for RPA2 抗体 (pThr21) (ABIN7138802)

抗原

See all RPA2 抗体
RPA2 (Replication Protein A2, 32kDa (RPA2))

适用

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宿主

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克隆类型

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多克隆

标记

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This RPA2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    pThr21

    原理

    Phospho-RPA2 (Thr21) Antibody

    交叉反应

    小鼠, 大鼠

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of Threonine 21(G-Y-T(p)-Q-S) derived from Human RFA2.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    RPA2 (Replication Protein A2, 32kDa (RPA2))

    别名

    RPA2

    背景

    Background: Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions. Required for the efficient recruitment of the DNA double-strand break repair factor RAD51 to chromatin in response to DNA damage. Ref.9 Ref.14 Ref.15 Ref.16Functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair, it does not support chromosomal DNA replication and cell cycle progression through S-phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.

    Aliases: 60S acidic ribosomal protein P1 antibody, AA409079 antibody, AI325195 antibody, AU020965 antibody, ik:tdsubc_2g1 antibody, M(2)21C antibody, MGC137236 antibody, OTTHUMP00000004008 antibody, p32 antibody, p34 antibody, RCJMB04_6d17 replication protein A2, 32 kDa antibody, REPA2 antibody, Replication factor A protein 2 antibody, Replication protein A 32 kDa subunit antibody, Replication protein A 32 kDa subunit antibody, Replication protein A 34 kDa subunit antibody, Replication protein A antibody, Replication Protein A2 (32 kDa) antibody, Replication protein A2 antibody, Replication protein A2, 32 kDa antibody, RF-A protein 2 antibody, Rf-A2 antibody, RFA antibody, RFA2_HUMAN antibody, RP-A p32 antibody, RP-A p34 antibody, RP21C antibody, RPA 2 antibody, RPA 32 antibody, RPA antibody, Rpa2 antibody, RPA32 antibody, RPA34 antibody, RpLP1 antibody, RpP2 antibody, xx:tdsubc_2g1 antibody, zgc:109822 antibody

    UniProt

    P15927

    途径

    Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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