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FAK 抗体 (pSer843)

PTK2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7138762
发货至: 中国
  • 抗原 See all FAK (PTK2) 抗体
    FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))
    抗原表位
    • 43
    • 33
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer843
    适用
    • 326
    • 274
    • 205
    • 21
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    • 6
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    • 1
    • 1
    • 1
    宿主
    • 335
    • 15
    • 3
    • 2
    • 1
    • 1
    克隆类型
    • 329
    • 28
    多克隆
    标记
    • 155
    • 17
    • 16
    • 12
    • 10
    • 10
    • 10
    • 10
    • 10
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    • 10
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    • 1
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    This FAK antibody is un-conjugated
    应用范围
    • 289
    • 133
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    • 120
    • 105
    • 68
    • 60
    • 42
    • 31
    • 28
    • 23
    • 5
    • 2
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    Western Blotting (WB), ELISA
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
    免疫原
    Peptide sequence around phosphorylation site of serine843(R-G-S(p)-I-D) derived from Human FAK .
    亚型
    IgG
    Top Product
    Discover our top product PTK2 Primary Antibody
  • 应用备注
    WB:1:500-1:1000,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))
    别名
    PTK2 (PTK2 产品)
    背景

    Background:

    Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity.

    Jiang X, Sinnett-Smith J, Rozengurt E (2007)Cell Signal 19, 1000-10 . Jacamo R, Jiang X, Lunn JA, Rozengurt E (2007)J Cell Physiol 210, 436-44. Le Boeuf F, Houle F, Sussman M, Huot J (2006)Mol Biol Cell 17, 3508-20 .

    Aliases: FADK 1 antibody, FADK antibody, FAK related non kinase polypeptide antibody, FAK1 antibody, FAK1_HUMAN antibody, Focal adhesion kinase 1 antibody, Focal adhesion Kinase antibody, Focal adhesion kinase isoform FAK Del33 antibody, Focal adhesion kinase related nonkinase antibody, FRNK antibody, p125FAK antibody, pp125FAK antibody, PPP1R71 antibody, Protein phosphatase 1 regulatory subunit 71 antibody, Protein tyrosine kinase 2 antibody, Protein-tyrosine kinase 2 antibody, Ptk2 antibody, PTK2 protein tyrosine kinase 2 antibody

    UniProt
    Q05397
    途径
    Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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