Girdin 抗体 (pSer417)
Quick Overview for Girdin 抗体 (pSer417) (ABIN7138609)
抗原
See all Girdin (CCDC88A) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer417
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交叉反应
- 人, 小鼠
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纯化方法
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
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免疫原
- Peptide sequence around phosphorylation site of Serine 417(L-E-M(p)-A-Q) derived from Human Girdin .
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亚型
- IgG
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应用备注
- IHC:1:50-1:100,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))
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别名
- CCDC88A
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背景
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Background:
girdin IS a ubiquitously expressed actin binding protein that plays an important role in the formation of stress fibers and lamellipodia. Subsequent to phosphorylation by Akt, Girdin accumulates at the leading edge of migrating cells and appears to be crucial for the integrity of the actin cytoskeleton and for cell migration.
Enomoto A., Dev. Cell 9:389-402(2005).
Simpson F., Traffic 6:442-458(2005).
Hillier L.W., Nature 434:724-731(2005).Aliases: AKT iphosphorylation enhancer antibody, Akt phosphorylation enhancer antibody, APE antibody, Ccdc88a antibody, Coiled coil domain containing 88A antibody, Coiled coil domain containing protein 88A antibody, Coiled-coil domain-containing protein 88A antibody, FLJ10392 antibody, G alpha interacting vesicle associated protein antibody, G alpha-interacting vesicle-associated protein antibody, Galpha interacting vesicle associated protein antibody, Girders of actin filament antibody, Girdin antibody, GIV antibody, GRDN antibody, GRDN_HUMAN antibody, HkRP1 antibody, Hook related protein 1 antibody, Hook-related protein 1 antibody, KIAA1212 antibody
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UniProt
- Q3V6T2
抗原
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