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Nibrin 抗体 (pSer343)

This anti-Nibrin antibody is a 兔多克隆 antibody detecting Nibrin in WB 和 ELISA. Suitable for 人.

Western blot analysis of extracts from Hela cells untreated or treated with Hydroxyurea using p95/NBS1(Phospho-Ser343) Antibody. (Nibrin 抗体 (pSer343))

1 image

产品编号 ABIN7138565

发货至: 中国

Datasheet as PDF

Quick Overview for Nibrin 抗体 (pSer343) (ABIN7138565)

抗原

See all Nibrin (NBN) 抗体

Nibrin (NBN)

适用

94
61
35
2
1
1
1
1

人

宿主

兔

克隆类型

多克隆

标记

69
7
5
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1

This Nibrin antibody is un-conjugated

应用范围

104
41
31
29
27
26
22
16
15
12
6
4
2
2
1

Western Blotting (WB), ELISA

Discover our top product NBN Primary Antibody

抗原表位
38

15

10

8

4

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer343

交叉反应

人

纯化方法

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

免疫原

Peptide sequence around phosphorylation site of serine 343 (S-L-S(p)-Q-G) derived from Human p95/NBS1.

亚型

IgG
anti-Nibrin (NBN) (AA 467-615) antibody
NBN 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 7E4C2 unconjugated

anti-Nibrin (NBN) (AA 183-460) antibody
NBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 8E7 unconjugated

anti-Nibrin (NBN) (AA 461-754) antibody
NBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3A9 unconjugated

anti-Nibrin (NBN) (AA 461-754) antibody
NBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3A2 unconjugated

anti-Nibrin (NBN) (AA 183-460) antibody
NBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 6E11 unconjugated

anti-Nibrin (NBN) (AA 183-460) antibody
NBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2F5 unconjugated

anti-Nibrin (NBN) (AA 435-754) antibody
NBN 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Nibrin (NBN) (AA 645-754) antibody
NBN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E4 unconjugated

anti-Nibrin (NBN) antibody
KO Validated NBN 适用: 人 WB, IF, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Nibrin (NBN) (AA 714-745), (C-Term) antibody
NBN 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB:1:500-1:1000,

限制

仅限研究用
状态

Liquid

缓冲液

Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C,-80 °C

储存方法

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
抗原

Nibrin (NBN)

别名

NBN

背景

Background: Mutations in p95/NBS1 gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

Hsu HL, et al (2005) Oncogene, 24(31): 4956-64.
Falck J, et al. (2005) Nature, 434(7033): 605-11.
Buscemi G, et al. (2004) Oncogene, 23(46): 7691-700.
Beausoleil SA, et al. (2004) Proc Natl Acad Sci U S A, 101(33): 12130-5.
Aliases: AT V1 antibody, AT V2 antibody, ATV antibody, Cell cycle regulatory protein p95 antibody, FLJ10155 antibody, MGC87362 antibody, Nbn antibody, NBN_HUMAN antibody, NBS 1 antibody, NBS antibody, NBS1 antibody, Nibrin antibody, Nijmegen breakage syndrome 1 (nibrin) antibody, Nijmegen breakage syndrome antibody, Nijmegen breakage syndrome protein 1 antibody, p95 antibody, p95 protein of the MRE11/RAD50 complex antibody

UniProt

O60934

途径

DNA Damage Repair, Production of Molecular Mediator of Immune Response

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