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MAP2K5 抗体 (pSer311, pThr315)

This 兔 多克隆 anti-MAP2K5 antibody specifically detects MAP2K5 in WB 和 ELISA. The antibody is reactive with 大鼠 samples.
产品编号 ABIN7138546
发货至: 中国
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Quick Overview for MAP2K5 抗体 (pSer311, pThr315) (ABIN7138546)

抗原

See all MAP2K5 抗体
MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))

适用

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大鼠

宿主

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克隆类型

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多克隆

标记

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This MAP2K5 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    pSer311, pThr315

    原理

    Phospho-Map2k5 (Ser311/Thr315) Antibody

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of Serine 311 and threonine 315 (V-N-S(p)I-A-K-T(p)-Y-V) derived from Rat MEK5.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))

    别名

    Map2k5

    背景

    Background: Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appear to play a critical role in protecting cells from stress-induced apopotosis, neuronal survival and cardiac development and angiogenesis.

    English J.M., Vanderbilt C.A., Xu S., Marcus S., Cobb M.H.J. Biol. Chem. 270:28897-28902(1995)

    Aliases: Map2k5 antibody, Mek5 antibody, Mkk5 antibody, Prkmk5 antibody, Dual specificity mitogen-activated protein kinase kinase 5 antibody, MAP kinase kinase 5 antibody, MAPKK 5 antibody, EC 2.7.12.2 antibody, MAPK/ERK kinase 5 antibody, MEK 5 antibody

    UniProt

    Q62862

    途径

    MAPK Pathway, Neurotrophin Signaling Pathway
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