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IGF2R 抗体 (pSer2409)

This anti-IGF2R antibody is a 兔 多克隆 antibody detecting IGF2R in WB, IHC 和 ELISA. Suitable for 人.
产品编号 ABIN7138501
发货至: 中国

Quick Overview for IGF2R 抗体 (pSer2409) (ABIN7138501)

抗原

See all IGF2R 抗体
IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

适用

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宿主

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克隆类型

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多克隆

标记

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This IGF2R antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    pSer2409

    交叉反应

    人, 小鼠

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of Serine 2409(Q-D-S(p)-E-D) derived from Human IGF2R.

    亚型

    IgG
  • 应用备注

    WB:1:500-1:1000, IHC:1:50-1:100,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

    别名

    IGF2R

    背景

    Background:

    Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.

    Morgan D.O., Nature 329:301-307(1987).
    Oshima A., J. Biol. Chem. 263:2553-2562(1988).
    Killian J.K., Mamm. Genome 10:74-77(1999)

    Aliases: 300 kDa mannose 6 phosphate receptor antibody, 300 kDa mannose 6-phosphate receptor antibody, Cation independent mannose 6 phosphate receptor antibody, Cation-independent mannose-6-phosphate receptor antibody, CD222 antibody, CD222 antigen antibody, CI Man 6 P receptor antibody, CI Man-6-P receptor antibody, CI MPR antibody, CI-M6PR antibody, CI-MPR antibody, CIMPR antibody, IGF 2 receptor antibody, IGF 2R antibody, IGF II receptor antibody, IGF-II receptor antibody, IGF2 receptor antibody, Igf2r antibody, Insulin like growth factor 2 receptor antibody, Insulin like growth factor II receptor antibody, Insulin-like growth factor 2 receptor antibody, Insulin-like growth factor II receptor antibody, M6P R antibody, M6P/IGF2 receptor antibody, M6P/IGF2R antibody, M6PR antibody, mannose 6 phosphate receptor antibody, mannose 6 phosphate receptor, cation independent antibody, MPR 300 antibody, MPR300 antibody, MPRI antibody, MPRI_HUMAN antibody

    UniProt

    P11717
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