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PAK2 抗体 (pSer197)

This anti-PAK2 antibody is a 兔 多克隆 antibody detecting PAK2 in ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7138464
发货至: 中国

Quick Overview for PAK2 抗体 (pSer197) (ABIN7138464)

抗原

See all PAK2 抗体
PAK2 (P21-Activated Kinase 2 (PAK2))

适用

  • 94
  • 47
  • 45
  • 3
  • 1
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宿主

  • 91
  • 4

克隆类型

  • 80
  • 15
多克隆

标记

  • 62
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 1
  • 1
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This PAK2 antibody is un-conjugated

应用范围

  • 62
  • 49
  • 29
  • 16
  • 6
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  • 3
  • 2
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ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 12
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    • 2
    • 2
    • 2
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    pSer197

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    免疫原

    Peptide sequence around phosphorylation site of Serine 197(T-R-S(p)-V-I) derived from Human PAK2.

    亚型

    IgG
  • 应用备注

    IHC:1:50-1:100,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    PAK2 (P21-Activated Kinase 2 (PAK2))

    别名

    PAK2

    背景

    Background:

    The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.

    Martin G.A., EMBO J. 14:1970-1978(1995).
    The MGC Project Team, Genome Res. 14:2121-2127(2004).
    Olsen J.V., Cell 127:635-648(2006).

    Aliases: C-t-PAK2 antibody, CB422 antibody, EC 2.7.11.1 antibody, Gamma PAK antibody, Gamma-PAK antibody, hPAK65 antibody, Kinase antibody, p21 (CDKN1A) activated kinase 2 antibody, p21 (CDKN1A)-activated kinase 2a antibody, p21 activated kinase 2 antibody, p21 protein (Cdc42/Rac)-activated kinase 2 antibody, p21 protein Cdc42 Rac activated kinase 2 antibody, p21-activated kinase 2 antibody, p21-activated kinase, 65-KD antibody, p21-activated protein kinase I antibody, p21CDKN1A activated kinase 2 antibody, p27 antibody, p34 antibody, p58 antibody, p65PAK antibody, PAK 2 antibody, PAK-2 antibody, PAK-2p34 antibody, Pak2 antibody, PAK2_HUMAN antibody, PAK65 antibody, PAKgamma antibody, S6 H4 kinase antibody, S6/H4 kinase antibody, Serine threonine protein kinase PAK 2 antibody, Serine/threonine protein kinase PAK 2 antibody

    UniProt

    Q13177

    途径

    MAPK Pathway, RTK signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
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