Cytochrome C 抗体 (AA 71-75)
Quick Overview for Cytochrome C 抗体 (AA 71-75) (ABIN7138333)
抗原
See all Cytochrome C (CYCS) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 71-75
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Affinity purification
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免疫原
- Peptide sequence around aa.71-75(N-P-K-K-Y) derived from Human Cytochrome C.
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亚型
- IgG
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应用备注
- WB:1:500-1:1000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified Rabbit polyclonal in PBS( pH 7.4) containing with 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
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别名
- CYCS
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背景
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Background: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.Aliases: CYC, HCS, THC4,
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UniProt
- P99999
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途径
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
抗原
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