EPAS1 抗体 (AA 547-551)
Quick Overview for EPAS1 抗体 (AA 547-551) (ABIN7138289)
抗原
See all EPAS1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 547-551
-
交叉反应
- 人
-
纯化方法
- Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
-
免疫原
- Peptide sequence around aa.547-551(P-E-E-R-L) derived from HumanHIF2A.
-
亚型
- IgG
-
-
anti-Endothelial PAS Domain Protein 1 (EPAS1) (AA 339-541) antibody
EPAS1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Endothelial PAS Domain Protein 1 (EPAS1) (AA 21-336) antibodyEPAS1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Endothelial PAS Domain Protein 1 (EPAS1) (Ser343) antibodyEPAS1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Endothelial PAS Domain Protein 1 (EPAS1) (AA 680-870) antibodyEPAS1 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 1H3E12 unconjugated
anti-Endothelial PAS Domain Protein 1 (EPAS1) (C-Term) antibodyEPAS1 适用: 人, 大鼠, 小鼠, 鱼 WB, IHC, ELISA, IP, ICC, FACS, IF, ChIP, GS 宿主: 兔 Polyclonal unconjugated
anti-Endothelial PAS Domain Protein 1 (EPAS1) (AA 28-347) antibodyEPAS1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G2 unconjugated
anti-Endothelial PAS Domain Protein 1 (EPAS1) (AA 588-870) antibodyEPAS1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Endothelial PAS Domain Protein 1 (EPAS1) antibodyEPAS1 适用: 人 WB, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Endothelial PAS Domain Protein 1 (EPAS1) (AA 535-631) antibodyEPAS1 适用: 人, 大鼠, 小鼠, Hamster WB, IHC, ELISA, IP, ICC, FACS, IF, ChIP 宿主: 小鼠 Monoclonal ep190b unconjugated
anti-Endothelial PAS Domain Protein 1 (EPAS1) (AA 1-130) antibodyEPAS1 适用: 人, 大鼠, 小鼠, 猴, 绵羊 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB:1:500-1:1000,
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))
-
别名
- EPAS1
-
背景
-
Background:
Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation seems to require recruitment of transcriptional coactivators such as CREBPB and probably EP300. Interaction with redox regulatory protein APEX seems to activate CTAD.
Aliases: Basic helix loop helix PAS protein MOP2 antibody; Basic-helix-loop-helix-PAS protein MOP2 antibody; bHLHe73 antibody; Class E basic helix-loop-helix protein 73 antibody; ECYT4 antibody; Endothelial PAS domain containing protein 1 antibody; Endothelial pas domain protein 1 antibody; Endothelial PAS domain-containing protein 1 antibody; EPAS 1 antibody; EPAS-1 antibody; EPAS1 antibody; EPAS1_HUMAN antibody; HIF 1 alpha like factor antibody; HIF 2 alpha antibody; HIF-1-alpha-like factor antibody; HIF-2-alpha antibody; HIF2-alpha antibody; HIF2A antibody; HLF antibody; Hypoxia inducible factor 2 alpha antibody; Hypoxia inducible factor 2 alpha subunit antibody; Hypoxia-inducible factor 2-alpha antibody; Member of PAS protein 2 antibody; Member of pas superfamily 2 antibody; MOP 2 antibody; MOP2 antibody; PAS domain-containing protein 2 antibody; PASD2 antibody
-
UniProt
- Q99814
-
途径
- Signaling Events mediated by VEGFR1 and VEGFR2, Warburg Effect
抗原
-
