CYFIP2 抗体
Quick Overview for CYFIP2 抗体 (ABIN7129118)
抗原
See all CYFIP2 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠
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纯化方法
- Antigen affinity purification
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免疫原
- Fusion protein of Human CYFIP2
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亚型
- IgG
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anti-Cytoplasmic FMR1 Interacting Protein 2 (CYFIP2) (AA 1171-1220) antibody
CYFIP2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cytoplasmic FMR1 Interacting Protein 2 (CYFIP2) antibodyCYFIP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytoplasmic FMR1 Interacting Protein 2 (CYFIP2) (AA 733-820) antibodyCYFIP2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cytoplasmic FMR1 Interacting Protein 2 (CYFIP2) (AA 733-820) antibodyCYFIP2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G6 unconjugated
anti-Cytoplasmic FMR1 Interacting Protein 2 (CYFIP2) (C-Term) antibodyCYFIP2 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CYFIP2 (Cytoplasmic FMR1 Interacting Protein 2 (CYFIP2))
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别名
- CYFIP2
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背景
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Background: CYFIP2 (Cytoplasmic FMR1-interacting protein 2, p53-inducible protein 121) is a 1,278 amino acid protein encoded by the human gene CYFIP2. CYFIP2 belongs to the CYFIP family and is involved in T-cell adhesion and p53-dependent induction of apoptosis. It interacts with FMR1, FXR1 and FXR2 and is a component of the WAVE1 complex composed of Abi-2, CYFIP2, C3orf10/HSPC300, NAP125 and WASF1/WAVE1. Upon binding to activated Rac 1, CYFIP2 causes the complex to dissociate, releasing activated WASF1. The CYFIP2 promoter contains a p53-responsive element that confers p53 binding as well as transcriptional activation of a heterologous reporter. Induced expression of CYFIP2 is sufficient for caspase activation and cellular apoptosis, reminiscent of p53 activation.
Aliases: CYFIP2 antibody, KIAA1168 antibody, PIR121Cytoplasmic FMR1-interacting protein 2 antibody, p53-inducible protein 121 antibody
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UniProt
- Q96F07
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途径
- RTK signaling, Apoptosis, Positive Regulation of Endopeptidase Activity
抗原
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