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Recombinant SMAD2 抗体 (pSer255)

This anti-SMAD2 antibody is a 兔 单克隆 antibody detecting SMAD2 in ELISA 和 IF. Suitable for 人.
产品编号 ABIN7127748
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant SMAD2 抗体 (pSer255) (ABIN7127748)

抗原

See all SMAD2 抗体
SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This SMAD2 antibody is un-conjugated

应用范围

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ELISA, Immunofluorescence (IF)

克隆位点

2A12
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    pSer255

    原理

    Phospho-SMAD2 (S255) Recombinant Monoclonal Antibody

    纯化方法

    Affinity-chromatography

    免疫原

    A synthesized peptide derived from human Phospho-SMAD2 (S255)

    亚型

    IgG
  • 应用备注

    IF:1:20-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))

    别名

    SMAD2

    背景

    Background: Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.

    Aliases: Mothers against decapentaplegic homolog 2, MAD homolog 2, Mothers against DPP homolog 2, JV18-1, Mad-related protein 2, hMAD-2, SMAD family member 2, SMAD 2, Smad2, hSMAD2, SMAD2, MADH2, MADR2

    UniProt

    Q15796

    途径

    Cell Division Cycle, Hormone Transport, Chromatin Binding, Protein targeting to Nucleus
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