Recombinant MAPT 抗体 (pThr231)
Quick Overview for Recombinant MAPT 抗体 (pThr231) (ABIN7127712)
抗原
See all MAPT 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- pThr231
-
交叉反应
- 人
-
纯化方法
- Affinity-chromatography
-
免疫原
- A synthesized peptide derived from human Phospho-MAPT (T231)
-
亚型
- IgG
-
-
-
-
应用备注
- Recommended dilution: WB:1:500-1:5000,
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- MAPT (Microtubule-Associated Protein tau (MAPT))
-
别名
- MAPT
-
背景
-
Background: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Aliases: Microtubule-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, MAPT, MAPTL, MTBT1, TAU
-
UniProt
- P10636
-
途径
- MAPK Pathway, Microtubule Dynamics, M Phase, Regulation of Cell Size
抗原
-