Recombinant XPO1 抗体
Quick Overview for Recombinant XPO1 抗体 (ABIN7127436)
抗原
See all XPO1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人
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纯化方法
- Affinity-chromatography
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免疫原
- A synthesized peptide derived from human CRM1
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亚型
- IgG
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anti-Exportin 1 (XPO1) (AA 966-1071) antibody
XPO1 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, IF, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Exportin 1 (XPO1) (AA 625-845) antibodyXPO1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Exportin 1 (XPO1) (C-Term) antibodyXPO1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 斑马鱼, 兔, Pig, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Exportin 1 (XPO1) (AA 917-1071) antibodyXPO1 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Exportin 1 (XPO1) antibodyXPO1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Exportin 1 (XPO1) (AA 701-800) antibodyXPO1 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Exportin 1 (XPO1) (acLys568) antibodyXPO1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Exportin 1 (XPO1) (acLys568) antibodyXPO1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Exportin 1 (XPO1) (AA 966-1071) antibodyXPO1 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, IF, ICC 宿主: 小鼠 Monoclonal 5G3 unconjugated
anti-Exportin 1 (XPO1) (AA 817-846), (C-Term) antibodyXPO1 适用: 人 FACS, IHC (p) 宿主: 兔 Polyclonal RB19972 unconjugated
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应用备注
- Recommended dilution: IHC:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- XPO1 (Exportin 1 (XPO1))
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别名
- XPO1
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背景
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Background: Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs. In the nucleus, in association with RANBP3, binds cooperatively to the NES on its target protein and to the GTPase RAN in its active GTP-bound form (Ran-GTP). Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Involved in U3 snoRNA transport from Cajal bodies to nucleoli. Binds to late precursor U3 snoRNA bearing a TMG cap. Several viruses, among them HIV-1, HTLV-1 and influenza A use it to export their unspliced or incompletely spliced RNAs out of the nucleus. Interacts with, and mediates the nuclear export of HIV-1 Rev and HTLV-1 Rex proteins. Involved in HTLV-1 Rex multimerization.
Aliases: Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog), XPO1, CRM1
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UniProt
- O14980
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途径
- M Phase
抗原
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