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Recombinant BMI1 抗体

This 兔 单克隆 antibody specifically detects BMI1 in WB, IHC 和 ELISA. It exhibits reactivity toward 人.
产品编号 ABIN7127369
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant BMI1 抗体 (ABIN7127369)

抗原

See all BMI1 抗体
BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

抗体类型

Recombinant Antibody

适用

  • 141
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  • 1
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宿主

  • 85
  • 54
  • 5

克隆类型

  • 75
  • 69
单克隆

标记

  • 81
  • 10
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  • 4
  • 3
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This BMI1 antibody is un-conjugated

应用范围

  • 112
  • 75
  • 39
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  • 11
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  • 5
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA

克隆位点

1F2
  • 原理

    BMI1 Recombinant Monoclonal Antibody

    纯化方法

    Affinity-chromatography

    免疫原

    A synthesized peptide derived from human Bmi1

    亚型

    IgG
  • 应用备注

    WB:1:500-1:5000, IHC:1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

    别名

    BMI1

    背景

    Background: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.

    Aliases: Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51), BMI1, PCGF4 RNF51

    UniProt

    P35226

    途径

    Cell Division Cycle, Autophagy
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