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Recombinant H2AFX 抗体 (H2AXS139ph)

This 兔 单克隆 anti-H2AFX antibody (Clone 1F10) specifically detects H2AFX in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7127309
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
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Quick Overview for Recombinant H2AFX 抗体 (H2AXS139ph) (ABIN7127309)

抗原

See all H2AFX 抗体
H2AFX (H2A Histone Family, Member X (H2AFX))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This H2AFX antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

1F10
  • 抗原表位

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    H2AXS139ph

    原理

    Phospho-Histone H2AX (S139) Recombinant Monoclonal Antibody

    纯化方法

    Affinity-chromatography

    免疫原

    A synthesized peptide

    亚型

    IgG
  • 应用备注

    WB:1:3000-1:10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    H2AFX (H2A Histone Family, Member X (H2AFX))

    别名

    Histone H2AX

    背景

    Background: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.

    Aliases: Histone H2AX, H2a/x, Histone H2A.X, H2AFX, H2AX

    UniProt

    P16104

    途径

    Telomere Maintenance, DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
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