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Recombinant p63 抗体 (AA 1-100)

TP63 适用: 人 ELISA, IHC (f), FACS, Coat 宿主: 兔 Monoclonal unconjugated Recombinant Antibody
产品编号 ABIN7127111
发货至: 中国
  • 抗原 See all p63 (TP63) 抗体
    p63 (TP63) (Tumor Protein P63 (TP63))
    抗体类型
    Recombinant Antibody
    抗原表位
    • 12
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    适用
    • 63
    • 24
    • 22
    • 4
    • 2
    • 2
    宿主
    • 48
    • 19
    • 1
    克隆类型
    • 43
    • 25
    单克隆
    标记
    • 53
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This p63 antibody is un-conjugated
    应用范围
    • 42
    • 29
    • 20
    • 13
    • 11
    • 9
    • 8
    • 8
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Flow Cytometry (FACS), Coating (Coat)
    特异性
    P40 antibody (antibody recognizing Np63 only) is an isoform of p63, is thought to function as a stem cell factor, responsible for maintaining cells in an uncommitted state with regenerative potential a role that may be recapitulated in tumors derived from these cells. p40 is normally expressed in the basal or progenitor cell layer of stratified epithelia (eg. squamous, urothelial, bronchial), basal cells of some glandular epithelia (eg. prostate), as well as myoepithelial cells of breast and salivary glands, trophoblasts and thymic epithelial cells. In tumor tissues, p40 expression is specific for squamous cell carcinoma. p40 is equivalent to p63 in sensitivity for lung squamous cell carcinoma, but it is markedly superior to p63 in specificity, which eliminates a potential pitfall of misinterpreting a p63-positive adenocarcinoma or unsuspected lymphoma as squamous cell carcinoma. p40 appears to be a more reliable marker for squamous cell carcinoma.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant fragment (around aa1-100) of human p40 protein (exact sequence is proprietary)
    亚型
    IgG
    Top Product
    Discover our top product TP63 Primary Antibody
  • 应用备注

    Known_Application: ELISA (For coating, order antibody without BSA), Flow Cytometry (1-2 μg/million cells), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: HEK293, MDA-MB453 or MCF7 cells. Human prostate, lung or bladder squamous cell carcinoma tissue.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    p63 (TP63) (Tumor Protein P63 (TP63))
    别名
    TP63 (TP63 产品)
    别名
    AIS antibody, B(p51A) antibody, B(p51B) antibody, EEC3 antibody, KET antibody, LMS antibody, NBP antibody, OFC8 antibody, RHS antibody, SHFM4 antibody, TP53CP antibody, TP53L antibody, TP73L antibody, p40 antibody, p51 antibody, p53CP antibody, p63 antibody, p73H antibody, p73L antibody, TP63 antibody, tp63 antibody, DNp63 antibody, id:ibd3516 antibody, tp73l antibody, wu:fc89f04 antibody, wu:fk85h07 antibody, wu:fk88b02 antibody, Ket antibody, P73l antibody, Tp73l antibody, Trp63 antibody, TRP63 antibody, AI462811 antibody, P51/P63 antibody, P63 antibody, Tp63 antibody, Trp53rp1 antibody, Xp63 antibody, ket antibody, np63 antibody, tp73l-A antibody, trp63 antibody, tumor protein p63 antibody, transformation related protein 63 antibody, tumor protein p63 L homeolog antibody, TP63 antibody, tp63 antibody, Tp63 antibody, Trp63 antibody, tp63.L antibody
    背景
    Amplified in squamous cell carcinoma (AIS), Chronic ulcerative stomatitis protein (CUSP), EEC3, TP73L, LMS, TP63, Keratinocyte transcription factor KET, NBP, P51/P63, p53 like transcription factor, RHS, SHFM4, TAp63alpha, TP53CP, TP53L, Transformation-related protein 63, Trp53rp1, Trp6,3, Tumor protein p53-like, tumor protein p73-like,p40 (Squamous, Basal & Myoepithelial Cell Marker)
    Cellular localisation: Nucleus.
    分子量
    63kDa
    基因ID
    8626, 137569
    UniProt
    Q9H3D4
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