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FGF23 抗体 (AA 25-251)

This anti-FGF23 antibody is a 小鼠 单克隆 antibody detecting FGF23 in IHC (f). Suitable for 人.
产品编号 ABIN7127080
发货至: 中国

Quick Overview for FGF23 抗体 (AA 25-251) (ABIN7127080)

抗原

See all FGF23 抗体
FGF23 (Fibroblast Growth Factor 23 (FGF23))

适用

  • 72
  • 24
  • 17

宿主

  • 64
  • 32
  • 2
小鼠

克隆类型

  • 68
  • 30
单克隆

标记

  • 58
  • 13
  • 6
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This FGF23 antibody is un-conjugated

应用范围

  • 61
  • 37
  • 36
  • 24
  • 23
  • 9
  • 7
  • 6
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
  • 抗原表位

    • 18
    • 9
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 25-251

    特异性

    Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Additional members of the FGF family include the oncogenes FGF-3 (Int2) and FGF-4 (hst/Kaposi), FGF-5, FGF-6, FGF-7 (KGF), FGF-8 (AIGF), FGF-9 (GAF) and FGF-10 through FGF-23. Members of the FGF family share 30-55 % amino acid sequence identity and similar gene structure, and are capable of transforming cultured cells when overexpressed in transfected cells. Cellular receptors for FGFs are members of a second multigene family, including four tyrosine kinases designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant fragment (around aa25-251) of human FGF23 protein (exact sequence is proprietary)

    亚型

    IgG2b
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Human kidney tissue.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    FGF23 (Fibroblast Growth Factor 23 (FGF23))

    别名

    FGF23

    背景

    ADHR, FGF-23, FGFN, Fibroblast growth factor 23, HPDR2, HYPF, Phosphatonin, PHPTC, Tumor-derived hypophosphatemia-inducing factor,FGF23 (Fibroblast Growth Factor 23)
    Cellular localisation: Secreted (extracellular)

    分子量

    12-32kDa

    基因ID

    8074, 287370

    UniProt

    Q9GZV9

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion
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