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FGF23 抗体

There is 1 publication for this product available. The 小鼠 单克隆 anti-FGF23 antibody is suitable to detect FGF23 in samples from 人. It has been validated for WB, IHC 和 ELISA.
产品编号 ABIN1169432
发货至: 中国
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Quick Overview for FGF23 抗体 (ABIN1169432)

抗原

See all FGF23 抗体
FGF23 (Fibroblast Growth Factor 23 (FGF23))

适用

  • 148
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人

宿主

  • 112
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小鼠

克隆类型

  • 110
  • 83
单克隆

标记

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This FGF23 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA

克隆位点

FG322-3
  • 原理

    anti-FGF-23 (human), mAb (FG322-3)

    特异性

    Recognizes human FGF-23. Does not cross-react with mouse FGF-23.

    无交叉反应

    小鼠

    交叉反应 (详细)

    Does not cross-react with mouse FGF-23.

    产品特性

    Monoclonal Antibody. Recognizes human FGF-23. Does not cross-react with mouse FGF-23. Isotype: Mouse IgG1kappa. Clone: FG322-3. Applications: ELISA, IHC, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. FGF-23 is a regulator of phosphate homeostasis. It upregulates EGR1 expression in the presence of KLBy. Acts directly on the parathyroid to decrease PTH secretion. Regulates the vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization. Defects in FGF-23 are the cause of autosomal dominant hypophosphataemic rickets (ADHR) and of hyperphosphatemic familial tumoral calcinosis (HFTC).

    过滤

    0.2 μm filtered

    免疫原

    Recombinant human FGF-23.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    0.2μm-filtered solution in PBS, pH 7.4.

    储存液

    Without preservative

    注意事项

    After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    +4°C

    -20°C

    Stable for at least 1 year after receipt when stored at -20°C.

    有效期

    12 months
  • Ferrari, Palleschi, Bartoli, Polli, Armiraglio, Parafioriti, Croci, Tosi: "Management of intrathoracic phosphaturic mesenchymal tumor by nonintubated uniportal video-assisted thoracic surgery in a fragile patient." in: Cancer reports (Hoboken, N.J.), Vol. 5, Issue 5, pp. e1500, (2022) (PubMed).

  • 抗原

    FGF23 (Fibroblast Growth Factor 23 (FGF23))

    别名

    FGF-23

    背景

    Alternate Names/Synonyms: Fibroblast Growth Factor 23, Tumor-derived Hypophosphatemia-inducing Factor

    Product Description: FGF-23 is a regulator of phosphate homeostasis. It upregulates EGR1 expression in the presence of KLBy. Acts directly on the parathyroid to decrease PTH secretion. Regulates the vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization. Defects in FGF-23 are the cause of autosomal dominant hypophosphataemic rickets (ADHR) and of hyperphosphatemic familial tumoral calcinosis (HFTC).

    UniProt

    Q9GZV9

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion
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