FGF23 抗体
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北京 101111
Quick Overview for FGF23 抗体 (ABIN1169432)
抗原
See all FGF23 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- anti-FGF-23 (human), mAb (FG322-3)
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特异性
- Recognizes human FGF-23. Does not cross-react with mouse FGF-23.
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无交叉反应
- 小鼠
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交叉反应 (详细)
- Does not cross-react with mouse FGF-23.
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产品特性
- Monoclonal Antibody. Recognizes human FGF-23. Does not cross-react with mouse FGF-23. Isotype: Mouse IgG1kappa. Clone: FG322-3. Applications: ELISA, IHC, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. FGF-23 is a regulator of phosphate homeostasis. It upregulates EGR1 expression in the presence of KLBy. Acts directly on the parathyroid to decrease PTH secretion. Regulates the vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization. Defects in FGF-23 are the cause of autosomal dominant hypophosphataemic rickets (ADHR) and of hyperphosphatemic familial tumoral calcinosis (HFTC).
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过滤
- 0.2 μm filtered
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免疫原
- Recombinant human FGF-23.
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亚型
- IgG1 kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.2μm-filtered solution in PBS, pH 7.4.
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储存液
- Without preservative
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注意事项
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
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+4°C
-20°C
Stable for at least 1 year after receipt when stored at -20°C.
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有效期
- 12 months
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: "Management of intrathoracic phosphaturic mesenchymal tumor by nonintubated uniportal video-assisted thoracic surgery in a fragile patient." in: Cancer reports (Hoboken, N.J.), Vol. 5, Issue 5, pp. e1500, (2022) (PubMed).
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- FGF23 (Fibroblast Growth Factor 23 (FGF23))
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别名
- FGF-23
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背景
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Alternate Names/Synonyms: Fibroblast Growth Factor 23, Tumor-derived Hypophosphatemia-inducing Factor
Product Description: FGF-23 is a regulator of phosphate homeostasis. It upregulates EGR1 expression in the presence of KLBy. Acts directly on the parathyroid to decrease PTH secretion. Regulates the vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization. Defects in FGF-23 are the cause of autosomal dominant hypophosphataemic rickets (ADHR) and of hyperphosphatemic familial tumoral calcinosis (HFTC).
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UniProt
- Q9GZV9
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion
抗原
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