Recombinant PODXL 抗体 (AA 310-447)
Quick Overview for Recombinant PODXL 抗体 (AA 310-447) (ABIN7126803)
抗原
See all PODXL 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 310-447
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特异性
- Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.
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交叉反应 (详细)
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant fragment of human Podocalyxin (around aa 310-447) (exact sequence is proprietary)
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亚型
- IgG1
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应用备注
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Known_Application: ELISA (For coating, order antibody without BSA),Optimal dilution for a specific application should be determined.
Positive_Control: HeLa, Raji or Jurkat cells. Human angiosarcoma or kidney tissue.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- PODXL (Podocalyxin-Like (PODXL))
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别名
- PODXL
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背景
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PODXL, PDXL, GCTM-2, Gp200, PCLP1, Pcx, Podocalyxin-like protein 1,Podocalyxin (PODXL) (Hematopoietic Stem Cell Marker)
Cellular localisation: Cell Surface and Cytoplasmic -
分子量
- 165-170kDa
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基因ID
- 5420, 732423
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UniProt
- O00592
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途径
- Tube Formation
抗原
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